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circar-e3 probe (catalog no. 715141)  (Advanced Cell Diagnostics Inc)

 
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    Advanced Cell Diagnostics Inc circar-e3 probe (catalog no. 715141)
    Circar E3 Probe (Catalog No. 715141), supplied by Advanced Cell Diagnostics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/circar-e3 probe (catalog no. 715141)/product/Advanced Cell Diagnostics Inc
    Average 90 stars, based on 1 article reviews
    circar-e3 probe (catalog no. 715141) - by Bioz Stars, 2026-05
    90/100 stars

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    circar-e3 probe (catalog no. 715141)  (Advanced Cell Diagnostics Inc)
    90
    Advanced Cell Diagnostics Inc circar-e3 probe (catalog no. 715141)
    Circar E3 Probe (Catalog No. 715141), supplied by Advanced Cell Diagnostics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/circar-e3 probe (catalog no. 715141)/product/Advanced Cell Diagnostics Inc
    Average 90 stars, based on 1 article reviews
    circar-e3 probe (catalog no. 715141) - by Bioz Stars, 2026-05
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    circar–e3 probe  (Advanced Cell Diagnostics Inc)
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    Advanced Cell Diagnostics Inc circar–e3 probe
    (A) Pearson correlation analysis showing strong positive correlations between circARs with AR-FL/-Vs. The blue gradient bar indicates the the scale of correlation coefficiency scores. (B) Schematic diagrams showing that the splice junctions that are specific to the most highly concordant <t>circAR/AR-V</t> pairs, <t>circAR-E3/AR-V9,</t> circAR-E2In1/AR-V3, and circAR-E2In2/AR-V3, are in close proximity.
    Circar–E3 Probe, supplied by Advanced Cell Diagnostics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/circar–e3 probe/product/Advanced Cell Diagnostics Inc
    Average 90 stars, based on 1 article reviews
    circar–e3 probe - by Bioz Stars, 2026-05
    90/100 stars
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    (A) Pearson correlation analysis showing strong positive correlations between circARs with AR-FL/-Vs. The blue gradient bar indicates the the scale of correlation coefficiency scores. (B) Schematic diagrams showing that the splice junctions that are specific to the most highly concordant circAR/AR-V pairs, circAR-E3/AR-V9, circAR-E2In1/AR-V3, and circAR-E2In2/AR-V3, are in close proximity.

    Journal: Oncogene

    Article Title: Circular RNAs add diversity to androgen receptor isoform repertoire in castration-resistant prostate cancer

    doi: 10.1038/s41388-019-0947-7

    Figure Lengend Snippet: (A) Pearson correlation analysis showing strong positive correlations between circARs with AR-FL/-Vs. The blue gradient bar indicates the the scale of correlation coefficiency scores. (B) Schematic diagrams showing that the splice junctions that are specific to the most highly concordant circAR/AR-V pairs, circAR-E3/AR-V9, circAR-E2In1/AR-V3, and circAR-E2In2/AR-V3, are in close proximity.

    Article Snippet: The custom-designed circAR–E3 probe (Catalog No. 715141) targeting the backsplice junction along with the positive (Catalog No. 710171) and negative (Catalog No. 701021) control probes were purchased from Advanced Cell Diagnostics.

    Techniques:

    (A) RT-qPCR analysis of nuclear and cytoplasmic RNA fractions showing predominant cytoplasmic localization of circARs in VCaP cells. Cytoplasmic-localized RPL30 and nuclear-localized 45S were used for comparison. The cytoplasmic to nuclear RNA ratios are plotted as ΔCt between the cytoplasmic and nuclear Ct values. (B & C) Two-dimensional (B) and three-dimensional (C) confocal fluorescence microscopy of circAR-E3 RISH showing predominant cytoplasmic localization of circAR-E3 in a LuCaP 35CR tumor. DAPI was used for nuclear staining. 3D images were composited from z-stack analysis.

    Journal: Oncogene

    Article Title: Circular RNAs add diversity to androgen receptor isoform repertoire in castration-resistant prostate cancer

    doi: 10.1038/s41388-019-0947-7

    Figure Lengend Snippet: (A) RT-qPCR analysis of nuclear and cytoplasmic RNA fractions showing predominant cytoplasmic localization of circARs in VCaP cells. Cytoplasmic-localized RPL30 and nuclear-localized 45S were used for comparison. The cytoplasmic to nuclear RNA ratios are plotted as ΔCt between the cytoplasmic and nuclear Ct values. (B & C) Two-dimensional (B) and three-dimensional (C) confocal fluorescence microscopy of circAR-E3 RISH showing predominant cytoplasmic localization of circAR-E3 in a LuCaP 35CR tumor. DAPI was used for nuclear staining. 3D images were composited from z-stack analysis.

    Article Snippet: The custom-designed circAR–E3 probe (Catalog No. 715141) targeting the backsplice junction along with the positive (Catalog No. 710171) and negative (Catalog No. 701021) control probes were purchased from Advanced Cell Diagnostics.

    Techniques: Quantitative RT-PCR, Comparison, Fluorescence, Microscopy, Staining

    (A) circAR-E3 is upregulated during castration-resistant progression of LuCaP PDX models. RISH was conducted on 3 different xenograft passages per PDX model. (B) Detection of circAR-E2 in plasma samples from 7 mCRPC patients. RT-PCR analysis was performed on RNA samples isolated from 0.25 ml of patient plasma. circGSE1 was used as a control circRNA that is present in the plasma.

    Journal: Oncogene

    Article Title: Circular RNAs add diversity to androgen receptor isoform repertoire in castration-resistant prostate cancer

    doi: 10.1038/s41388-019-0947-7

    Figure Lengend Snippet: (A) circAR-E3 is upregulated during castration-resistant progression of LuCaP PDX models. RISH was conducted on 3 different xenograft passages per PDX model. (B) Detection of circAR-E2 in plasma samples from 7 mCRPC patients. RT-PCR analysis was performed on RNA samples isolated from 0.25 ml of patient plasma. circGSE1 was used as a control circRNA that is present in the plasma.

    Article Snippet: The custom-designed circAR–E3 probe (Catalog No. 715141) targeting the backsplice junction along with the positive (Catalog No. 710171) and negative (Catalog No. 701021) control probes were purchased from Advanced Cell Diagnostics.

    Techniques: Reverse Transcription Polymerase Chain Reaction, Isolation